About Us

Genetic data driving therapeutic insights

We are a clinical-stage biotech informed by human genomics and phenotypic information at scale

23andMe Therapeutics is powered in part by genetic and phenotypic information from research-consented members of the 23andMe community, who we consider to be part of our team in our discovery and development efforts. With their participation, our researchers are able to identify and pursue novel targets that are central mediators of biological processes relevant to the immune system.

Leadership Team

CEO, Co-Founder

Anne Wojcicki

Anne is CEO and Co-Founder of 23andMe. Since co-founding 23andMe in 2006, Anne has pioneered the direct-to-consumer DNA testing space and the large-scale application of human genetic data to therapeutic development. As CEO, she has led the development of the only personal genetic test with FDA authorization to deliver health information directly to consumers, and the development of therapeutic programs and capabilities to address serious unmet medical needs.

 

Prior to founding 23andMe, Anne spent a decade on Wall Street investing in healthcare before pivoting to building a business that helps people prevent illness rather than profit from it. She received a B.S. in Biology from Yale University.

Head of Therapeutics Development

Jennifer Low, M.D., Ph.D.

Jennifer is the Head of Therapeutics Development at 23andMe. She oversees the transition of potential therapeutics from 23andMe's research laboratories into clinical development studies, and leads a group that includes preclinical and clinical development and drug manufacturing.

 

Jennifer has thirty years of drug development experience spanning academia, government, large pharma and small biotech. She has been the Chief Medical Officer at Loxo Oncology and has led early- and late-stage clinical development at Genentech/Roche that led to multiple drug approvals worldwide. She has degrees from Caltech, Georgetown, and Duke and has held academic positions at the National Cancer Institute and the National Naval Medical Center, where she was an attending physician for breast cancer patients. She has co-authored papers appearing in the New England Journal of Medicine, Science, Cancer Discovery, Journal of Clinical Oncology, and Nature Reviews Cancer.

Vice President, Human Genetics

Adam Auton, Ph.D.

Adam joined 23andMe in 2015 and is the Vice President of Human Genetics. Adam is responsible for computational approaches to target discovery via statistical genetics and machine learning approaches.

 

Prior to joining 23andMe, Adam pursued an academic career at Albert Einstein College of Medicine, with a focus on large-scale genomic analyses and statistical algorithm development. He received a MSci in Physics from the University of Bristol (UK), and a DPhil in Statistical and Population Genetics from the University of Oxford.

Our History

Realizing our vision for a different kind of biotech

Founding of 23andMe Therapeutics
2015
Concurrent with the 23andMe database surpassing one million genotypes, our therapeutics division was founded to enable our customer community to be part of addressing human disease. Led by former Genentech Head of Research and Early Development and Series A 23andMe investor Richard Scheller, 23andMe Therapeutics began building the talent and infrastructure to become an integrated biotechnology company with the vision to use genetics to predict, prevent, and treat disease.
23ME-00610 program begins
2017
The immunological checkpoint CD200R1 was identified as a target of interest through our immuno-oncology signature; 23andMe began target validation and antibody discovery for what would eventually become 23ME-00610.
GSK collaboration begins
2018
We embarked on an exclusive four-year collaboration with GSK that generated more than 50 programs across multiple therapeutic areas.
23ME-01473 program begins
2018
The NK cell-suppressing tumor cell protein ULBP6 was identified as a target of interest through our immuno-oncology signature. 23andMe began a number of laboratory investigations and started creating the antibody that would become 23ME-01473.
First GSK collaboration program enters the clinic
2020
GSK filed the Investigational New Drug Application for the joint 23andMe/GSK program directed to the molecule GSK6097608, an antibody targeting the CD96 receptor in patients with solid tumors, and the Phase 1 study commenced.
23ME-00610 enters the clinic
2022
Having received clearance of its first Investigational New Drug Application to the FDA as sponsor, 23andMe began dosing a group of 28 patients with advanced solid tumors in the dose escalation study of our wholly-owned immuno-oncology program targeting immunological checkpoint receptor CD200R1. Eventually 13 clinical sites in the US and Canada were added to the study.
GSK collaboration extended
2022
With more than 50 active programs generated, our exclusive collaboration with GSK was extended for an additional year under the terms of the agreement. GSK continued to lead development of GSK6097608, an immuno-oncology therapeutic mAb targeting CD96, while 23andMe chose to take a royalty option for this target.
23ME-00610 advances to the Phase 2 portion of the Phase 1/2a clinical trial
2023
23andMe announced that the Phase 1 dose escalation had been completed and a dose chosen for the Phase 2a portion of the ongoing Phase 1/2a clinical trial. The first Phase 2 patient in the solid tumor expansion cohorts was enrolled.
GSK collaboration evolves
2023
GSK renewed its relationship with 23andMe with a non-exclusive license to access the database. The end of our exclusive collaboration with GSK has enabled additional collaborations with companies interested in leveraging the 23andMe database, as well as our experience in interrogating it.
23ME-01473 enters the clinic
2024
23ME-01473, 23andMe Therapeutics’ second wholly owned immuno-oncology program receives IND clearance from the FDA.